A trainer wrapping a black elastic support strap around a bare ankle on a gym mat

The ankle sprain that never quite came right

THE ANKLE AFTER A SPRAIN

An ankle sprain is the injury nobody takes seriously, including the person who has it. It is also the injury most likely to be quietly still there a year later, and the one most likely to have been treated with nothing but time.

What actually happens to a first sprain, in numbers

A systematic review and meta-analysis pooled fifteen studies of people with a first lateral ankle sprain and no previous ankle injury. Following them forward:

  • Residual pain in 48.6% at three months, 21.5% at six months, and 6.7% at twelve months.
  • Subjective instability in 37.9% at three months, 16.1% at six, and 8.1% at twelve.
  • A recurrent sprain in 15.8% within twelve months.

Two readings of that are both correct. Most first sprains do settle, and the curve keeps improving all the way out to a year, which is why the authors suggest a longer period of non-operative treatment before anyone reaches for surgery. And a real minority does not settle — one ankle in fifteen still hurting at a year, one in six sprained again.

Why the ones that stall, stall

Three things, usually together. The ligament heals long, so the joint has more play than it should. The proprioceptive feedback from the joint never fully recovers, so the foot arrives at the ground in slightly the wrong position and the same ligament is loaded again. And the peroneal muscles that would have caught it are weak, because nobody rehabilitated them past the point where walking stopped hurting.

That is a loading and control problem before it is a tissue problem, and it is why the treatment that works at the ankle is rarely a needle. It is a program.

Underneath all three sits the same question we ask on every page of this site: what is the ligament repairing in? A ligament that healed long in a body with high inflammatory load, poor sleep and continued nicotine exposure healed long partly for that reason, and it will remodel under the same constraints next time unless they change. That is the first conversation, not the last, and what we measure is on the metabolic health page.

Which structure, before which treatment

The ankle punishes vague diagnosis more than most joints, because four different problems present as the same complaint. A chronically painful lateral ligament, a peroneal or posterior tibial tendinopathy, a sinus tarsi that has become a pain generator in its own right, and a worn tibiotalar joint surface are four separate targets with four separate answers. They are also physically small and sit close together, so anything delivered here is delivered under ultrasound and the record says which structure was entered.

The ligament and tendon targets are where the tendon literature applies, and that is a different body of evidence from the intra-articular literature — the same reason the knee evidence does not belong in a conversation about an ankle. Those targets are worked through on the tendinopathy page.

For the joint surface itself the honest position is that the case is made joint by joint rather than transferred from the knee, and that a worn tibiotalar joint is usually a post-traumatic joint with a loading problem underneath it. Correcting the loading and the terrain is the part with the best return here, and it is the part that most people arriving have never actually been given.

Why an ankle sprain is worth taking seriously twenty years out

The ankle is one of the three joints in the population estimate of post-traumatic osteoarthritis. Roughly 12% of symptomatic hip, knee and ankle osteoarthritis in the United States is post-traumatic, about 5.6 million people. Unlike the knee, the ankle rarely wears out on its own; when a tibiotalar joint is arthritic there is usually an event in the history. That is the argument for rehabilitating the sprain properly at month three rather than discovering the joint at year twenty.

What people ask about an old ankle injury

It has been a year and it still aches. Is that normal?

It is not the common outcome — residual pain was present in 6.7% at twelve months in the pooled data — but it is a real group, and it is the group worth assessing rather than waiting out further. What that assessment covers is on the what-to-expect page.

My ankle keeps giving way. Is that weakness or damage?

Usually both, in a loop: a ligament that healed long, proprioception that never came back, and peroneal muscles that stopped being trained when walking stopped hurting. Recurrent sprains occurred in 15.8% within a year, and the fix starts with loading rather than a needle — see the recovery timeline.

Will an injection help my ankle arthritis?

It depends entirely on whether the joint surface is the pain generator or the loading pattern and the surrounding soft tissue are, and that is settled by examination rather than assumed from a report. How the same question is worked through in a nearby tendon is on the Achilles page.

What about the tendons around the ankle?

That is a different target with a different literature behind it, and it is assessed and treated separately from the joint. The tendon side is covered on the tendinopathy page.

Does an old sprain really cause arthritis later?

The ankle is one of the three joints in the post-traumatic osteoarthritis estimate, and unlike the knee it seldom wears out without an event in the history. The longer-term trajectory after any joint injury is on the tissue timeline page.

For the foot and ankle

If an old ankle still decides what shoes you own, have it assessed

A sprain that never resolved is a treatable problem with a specific cause. Finding the cause is the appointment.

12174 Natural Bridge Rd, Suite 303
St. Louis, MO 63044
Next to DePaul Hospital, just off the 270 and 70 junction, west of the airport.

Sources

  • Michels F, Wastyn H, Pottel H, Stockmans F. The presence of persistent symptoms 12 months following a first lateral ankle sprain: a systematic review and meta-analysis. Foot Ankle Surg, 2022. PubMed 34961654 doi:10.1016/j.fas.2021.12.002
  • Brown TD, Johnston RC, Saltzman CL, et al. Posttraumatic osteoarthritis: a first estimate of incidence, prevalence, and burden of disease. J Orthop Trauma, 2006. PubMed 17106388 doi:10.1097/01.bot.0000246468.80635.ef
  • Hoeber S, Aly AR, Ashworth N, Rajasekaran S. Ultrasound-guided hip joint injections are more accurate than landmark-guided injections: a systematic review and meta-analysis. Br J Sports Med, 2016. PubMed 26062955 doi:10.1136/bjsports-2014-094570
  • Aly AR, Rajasekaran S, Ashworth N. Ultrasound-guided shoulder girdle injections are more accurate and more effective than landmark-guided injections: a systematic review and meta-analysis. Br J Sports Med, 2015. PubMed 25403682 doi:10.1136/bjsports-2014-093573
  • D'Souza RS, Her YF, Hussain N, et al. Evidence-based clinical practice guidelines on regenerative medicine treatment for chronic pain: a consensus report from a multispecialty working group. J Pain Res, 2024. PubMed 39282657 doi:10.2147/JPR.S480559
  • Leong HT, Fu SC, He X, et al. Risk factors for rotator cuff tendinopathy: a systematic review and meta-analysis. J Rehabil Med, 2019. PubMed 31489438 doi:10.2340/16501977-2598