A doctor attentively listens to a patient during a medical consultation, emphasizing care and understanding.

Dr. Gurpreet Singh Padda, MD, MBA, MHP

THE PHYSICIAN

Dr. Gurpreet Singh Padda, MD, MBA, MHP is a trauma-surgery-trained anesthesiologist who became an interventional pain physician, an addiction medicine specialist and an obesity medicine diplomate. He is a former Assistant Professor of Anesthesiology and Pediatrics and a former deputy director of a university institutional review board.

The correction that shaped the practice

He spent roughly the first twenty years of his career doing what he was trained to do: treating pain as a mechanical problem at the site where it hurt, and telling patients whose blood sugar was drifting that it was “not too bad.” He was wrong on both counts, and he says so in public rather than quietly revising.

What changed his mind was watching which patients did not get better. The ones whose pain outlasted a technically successful procedure were reliably the ones carrying metabolic disease — insulin resistance, visceral adiposity, disrupted sleep — alongside the injury. Pain, addiction, obesity and type 2 diabetes stopped looking like four problems and started looking like one collision of epidemics running on a shared engine.

What that means for a patient here

It means the tendon is not the whole appointment. It means a metabolic panel is part of planning a joint injection rather than a separate concern for a different doctor. And it means behavioral work is prescribed, in-house, with the same seriousness as a procedure — because the injection buys a window, and something has to fill it.

Beyond the clinic

He funds a 501(c)(3) foundation out of his own pocket, and has served on medical missions to Honduras, Guatemala and Nicaragua. Seva means service performed without expectation of return, credit or exchange. It is the reason a decision gets made, not a claim about how good the practice is.

Training and credentials

Trauma-surgery-trained anesthesiologist, interventional pain physician, addiction medicine specialist and obesity medicine diplomate. Former Assistant Professor of Anesthesiology and Pediatrics, and former deputy director of a university institutional review board — which is to say, someone who has spent time on the other side of the question of what counts as adequate evidence.

That IRB background is relevant to how this website is written. Someone who has sat in judgment on study protocols tends to be harder to impress with a press release, and it is part of why the pages here say plainly where the evidence thins.

The collision of epidemics

The organizing idea of the practice is that chronic pain, addiction, obesity and type 2 diabetes are not four separate specialties’ problems that happen to co-occur. They share an engine: metabolic inflammation, insulin resistance, disrupted reward signaling, and the environmental and economic conditions that drive all three.

A patient with a shoulder that will not heal, a rising A1C, five hours of broken sleep and a job they cannot modify is not presenting with four coincidences. Treating the shoulder alone is what produces a series of partial successes and a person who concludes nothing works.

What he has put on the record

He published the practice’s own opioid outcomes on International Overdose Awareness Day in August 2026 — 21% of patients completely off opioid pain medication within 90 days of active interventional treatment, 34% within one year, and the large majority of the remainder brought below 30 morphine milligram equivalents a day, from an average arrival dose above 90.

It is the same argument as the collision of epidemics above: the dose falls because the generator was treated and the terrain was changed, not because a taper was imposed on its own. Those are practice-reported figures from his own patient population, not trial outcomes, and individual results vary. Reported by AP News; the full release is here.

Why the behavioral work is delivered in-house

Acceptance and Commitment Therapy is provided here by a licensed, pain-trained behavioral clinician. It is not referred out, and it is not a leaflet at discharge. Behavioral and metabolic work is roughly 40–50% of the treatment protocol.

The reason is simple enough: a nervous system that has spent two years guarding a joint needs retraining as much as the tissue does, and a referral that happens somewhere else, months later, with a clinician who has not seen the imaging, does not accomplish that.

Seva

He funds a 501(c)(3) foundation out of his own pocket, and has served on medical missions to Honduras, Guatemala and Nicaragua. Seva means service performed without expectation of return, credit or exchange.

It is the reason certain decisions get made — treating people who cannot pay, building nonprofit structures that carry no revenue, telling someone their money is better spent elsewhere — rather than a claim about how good the practice is.

What this means when you are sitting in the room

You will be asked about things that do not obviously relate to your elbow. You will sometimes be told that the treatment you came in asking about is not a good bet for you. And if the honest answer is that you need a surgeon, or a rheumatologist, or a better night’s sleep more than you need an injection, that is what you will hear.

Related reading

The confession comes first, deliberately

Most physician biographies are a list of things that went right. This one leads with two decades of being wrong, because that is the more useful information about how someone practices.

He told pre-diabetic patients their A1C was “not too bad.” He treated pain as a mechanical problem at the site where it hurt. He was, for years, a strict vegetarian preaching the dietary guidelines he now dismantles. None of that was negligence — it was competent practice of what he had been taught, which is exactly why it is worth saying out loud.

A physician who has publicly changed his mind about something large is a physician who can change it again when the evidence moves. The alternative — a faultless authority who has never revised anything — is the register most patients in chronic pain have already been failed by several times.

How to reach him, and what to expect

Appointments are made through the clinic, and the assessment is described on the what to expect page. If you are a physician looking for a regenerative opinion on a complex patient, the referral page covers what comes back to you and when.

What people ask about Dr. Padda

Is Dr. Padda the person who will see me?

The assessment and injection are physician-delivered. What to expect.

What is MHP?

Metabolic Health Practitioner, through the Society of Metabolic Health Practitioners. Why that matters to a tendon.

Does he still practice interventional pain medicine?

Yes — this practice is one part of a broader pain and metabolic practice. Opioid stewardship.

Why does a PRP clinic ask about my blood sugar?

Because repair runs on metabolic substrate, and that is the difference between restarting a repair and asking one to fail twice. Candidacy.

Publications and outside work

Dr. Padda has published in the peer-reviewed literature and speaks publicly on metabolic health, pain and addiction — frequently on the argument that these fields have been artificially separated. He has served on the boards of Exoneration Nation, Arise Veterans, U Gro, the March of Dimes and the Deva Singh Foundation.

What he says he got wrong, specifically

The list he gives publicly is not vague. Treating pain as a local mechanical problem. Reassuring patients about blood sugar that was already drifting toward disease. Accepting dietary guidance he now argues contributed to the metabolic epidemic he treats. Believing that a technically excellent procedure was the whole of the job.

Each of those has a direct consequence for how a patient is handled here, which is the only reason any of it belongs on a clinic website.

The bite of beef that ended twenty years of certainty

He was a strict vegetarian, defending the dietary guidelines he now dismantles, until a beef on bun at Gates Bar-B-Q in Kansas City. That is a flippant way to date a serious reversal, and he tells it that way on purpose — because a physician who describes his own change of mind as a clean intellectual process is describing something that did not happen.

The reversal itself was not flippant. It meant accepting that he had spent two decades telling pre-diabetics their A1C was “not too bad,” and that the acellular carbohydrates and industrial seed oils he had considered neutral were doing measurable work on the patients who were not getting better.

He publishes that rather than quietly revising, because the alternative — faultless authority that has never been wrong about anything — is precisely the register his patients have already been failed by several times.

What he is actually angry about

Not patients, and not the physicians who prescribed in good faith under guidance that later reversed. The anger in this practice is pointed at incentives.

  • A food supply engineered against dopamine circuitry, subsidized into being the cheapest calories available and concentrated where the alternatives are fewest.
  • Medicalization — a payment system that funds the injection and the prescription but not the hour of behavioral work, which reliably produces care that milks the cow rather than curing it.
  • Symptom-based silos, in which four specialists each manage their region correctly and nobody owns the collision.
  • Loneliness, which is treated here as a primary driver of chronic pain and addiction rather than a soft factor — social disconnection raises inflammatory markers and lowers pain thresholds as measurably as any drug.

The enemy is always a system or an incentive. It is never the person sitting in the room, and it is never a colleague or another practice.

Health and wealth are one system

He is also a businessman — president of Red Pill Kapital, an ASC director, a restaurateur, coauthor of a bestselling book on building a life — and that is not a side interest that competes with the medicine. It is where the macroeconomic lens comes from.

The same operator’s eye that re-engineers a preadmission program is what notices that we subsidize the crop that causes the disease and then means-test the insulin. A patient bankrupted by their illness has not been treated, whatever happened to their imaging.

Ask him about your own case

Whether PRP is reasonable for you depends on your tissue, your metabolic health and what you have already tried. That is a conversation, not a form.

12174 Natural Bridge Rd, Suite 303
St. Louis, MO 63044